Injury and liver disease can occur from a variety of causes. Biopsy is done either by approaching the liver in-between the ribs or through a vein in the neck and advancing a thin tubing (catheter guided biopsy needle) into the liver. Patients are carefully selected to avoid and minimize risk of bleeding from the biopsy site. The process involves removing a tiny piece of liver by specialized needle and examining the tissue sample after proper processing and staining under a microscope.
Tests for Viral hepatitis A, B, C, Delta, E and other less commonĪ disease with abnormal storage of iron in liver and bodyĭisease: A disease characterized by accumulation of copper in liverĬancer: Screening test for alfa feto protein and imaging. Specific for certain diseases and biopsy of liver:Īre specific tests to identify the cause of underlying liver disease.Ī thorough medical history, clinical examination of the patients giveĪ clue to possible causev of the liver disease and then those testsĪre carried out to identify the causative agent.Īre some of the specific tests foe the causes of liver diseases: Varicose veins inside abdomen, collection of fluid in side the abdomen,Įnlargement of spleen and presence of liver tumor or cancer etc. Looking for nodular irregular liver, altered texture of the liver, abnormal Of liver, and presence of complications of liver disease. Tests usually are complimentary to assess the gross appearance /distortion Progresses and becomes established and chronic: That detect complications of liver disease that sets-in as the liver disease Poor ability to secrete bile and other Selective dysfunction Identifying the cause of liver damage will probably require more definitive and specific tests.Ĭommonly used tests for liver function include the measurements of the following in the blood:
#Liver issues full
Most of the time these tests do not indicate the actual cause of the liver injury or disease, they only suggest that the liver is not functioning to its full normal capacity and is injured or is diseased. When the liver does not function normally because of injury and disease the blood concentrations of theser substances deviate from their normal range. These tests essentially look for concentrations of certain elements or enzymes in the blood that are otherwise maintained within a tight range of normal values. These tests are based on normal functioning of liver.
Specific for certain diseases and biopsy of liver. That detect complications of liver disease that occurs as the liverĭisease progresses and becomes established and chronic.
Makes various substances/factors that prevent excessive bleeding.It plays key role in the metabolism of carbohydrates, fat, and proteins. Facilitates large number of metabolic processes of the body.Makes bile and pours it out into the gall bladder that helps digestion.Makes various proteins, essential vitamins, hormones and chemicals for normal body function.Acts as a filter for toxic substances and metabolizes various drugs and helps its elimination from the body.Shown below liver cells are arranged as plates or cords of cells withĬollection of vessels at the center and at outer rim of the radiatingįigure of normal liver as seen under microscope. Smaller branches of blood vessels that supply and drain blood into and
The connective tissue usuallyĪccounts for 5-10% of normal liver weight. The cell plates are supported in a matrix of small amount of fibrillar Liver has well organized layers or plates of cells called liver cells. The normal liver is brown in color, its surface is smooth band it is soft and pliable in texture. The gall bladder that stores bile, lies on its undersurface. Most of the liver is under the lower ribs and under normal conditions may not be felt by pressing on the abdomen except for its left portion that may be felt in the upper mid abdomen. It is a triangular or pyramid in shape and lies sideways in the upper right half of the abdomen with the base of the pyramid on the right side and the tip at the middle of the upper abdomen. It weighs about 1600 Gm in men and 1400 gm in women. The liver is the largest solid organ in human body. Specific for certain diseases and biopsy of liver That detect complications of liver disease